Ernest Y. Lee

MD/PhD Student

UCLA-Caltech Medical Scientist Training Program

David Geffen School of Medicine, UCLA

Henry Samueli School of Engineering and Applied Science, UCLA

Biography

Ernest Lee is a 6th year M.D./Ph.D. student in the UCLA-Caltech Medical Scientist Training Program and a 4th year graduate student in the Department of Bioengineering at UCLA under Dr. Gerard Wong. He received a B.S. in Physics with Honors from Caltech in 2012. He is interested in conducting research at the intersection of infectious, autoimmune, and neurodegenerative diseases, with a particular focus on machine-learning aided design of membrane-active antimicrobial peptides, anti-inflammatory strategies for autoimmune diseases, and the role of the nervous system in innate immune defense. He is a recipient of a 2017-2018 Early Career Research Grant from the National Psoriasis Foundation, a 2017-2018 NIAMS T32 Dermatology Scientist Training Program Grant, and a 2014-2015 and 2015-2016 NIGMS T32 Systems and Integrative Biology Training Program Grant.

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Interests

Biophysics
Innate Immunity
Antimicrobial Peptides
Autoimmune Diseases
Computational Biology
Neuroimmunology

Education

M.D. (Expected), 2020

University of California, Los Angeles
Ph.D. in Bioengineering, 2018

University of California, Los Angeles
B.S. in Physics (with Honors), 2012

California Institute of Technology

Publications

More Publications

Lee, Calvin K, de Anda, Jaime, Baker, Amy E, Bennett, Rachel R, Luo, Yun, Lee, Ernest Y, Keefe, Joshua A., Helali, Joshua S., Ma, Jie, Zhao, Kun, Golestanian, Ramin, O’Toole, George, Wong, Gerard C L. Multigenerational Memory and Adaptive Adhesion in Early Bacterial Biofilm Communities.. In Proc Natl Acad Sci USA: (2018), 2018.

Source Document

Takahashi, Toshiya, Kulkarni, Nikhil N, Lee, Ernest Y, Zhang, Ling-juan, Wong, Gerard C L, Gallo, Richard L. Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors.. In Scientific Reports 8(1):4032 (2018), 2018.

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Lee, Ernest Y, Lee, Michelle W, Wong, Gerard C L. Modulation of toll-like receptor signaling by antimicrobial peptides.. In Seminars in Cell & Developmental Biology: (2018), 2018.

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Lee, Michelle W, Lee, Ernest Y, Lai, Ghee Hwee, Kennedy, Nolan W, Posey, Ammon E, Xian, Wujing, Ferguson, Andrew L, Hill, R Blake, Wong, Gerard C L. Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission.. In ACS central science 3(11): 1156-1167 (2017), 2017.

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Lee, Ernest Y, Lee, Michelle W, Fulan, Benjamin M, Ferguson, Andrew L, Wong, Gerard C L. What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning?. In Interface focus 7(6): 20160153 (2017), 2017.

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